Figure 5

Figure 5

Transcriptional changes in cardiac factors in still heart mutants. A schematic representation of the altered expression of key cardiac transcription factors between wild-type (A) and still heart mutants (B). Genes such as gata4, gata5, hand2, and has2 exhibit significant changes in expression in the absence of Smyd1b. (Solid green line = directly activates transcription; dashed green line = indirectly or directly activates transcription; solid red line = directly inhibits transcription; dashed red line = indirectly or directly activates transcription; gray = absent; single green arrowhead = increased expression; double green arrowhead = significantly increased expression/production; single red arrowhead = decreased expression; double red arrowhead = significantly decreased expression).