|
Fig. 9 Bioinformatic analysis reveals phototransduction disruption and apoptosis in dync1h1−/− zebrafish at 5 dpf. (A) Pearson correlation analysis comparing WT and dync1h1−/− samples. (B) Volcano plot showing differential gene expression, with 1652 upregulated and 1856 downregulated genes (|log2 (FoldChange)|≥1 and adjusted P value ≤ 0.05). (C) Top Gene Ontology (GO) terms enriched among all differentially expressed genes. (D) Top KEGG pathways enriched among all differentially expressed genes. W1 to W3, three independent samples from the WT group; D1 to D3, three independent samples from dync1h1−/− group. WT, wild type.