Dysregulation of synaptic contacts in the OB caused by 6-OHDA. (A) Schematic diagram of a sagittal view of the OB, indicating three glomerular clusters: dorsal (dG), dorsolateral (dlG), and ventromedial (vmG). (B–E) Double immunohistochemistry of synaptic vesicle protein 2 (SV2) and tyrosine hydroxylase (TH) in sagittal sections of the OB from controls, 1 dpi, 3 dpi, and 7 dpi groups. Representative images taken from 5–7 animals analyzed per group. Dotted lines indicate the glomerular clusters selected. Whole bulb (B), and magnified views of: (C) dlG cluster, (D) dG cluster, and (E) vmG cluster. Green: Tbr2a; red: TH; blue: DAPI. Scale bars: 100 µm in (B); 50 µm in (C–E).
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