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Fig. 6

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ZDB-IMAGE-251231-6

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Shi et al., 2025 - Minoxidil ameliorates myelodysplastic syndrome by targeting Wnt4 while sparing normal hematopoiesis

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Figures for Shi et al., 2025

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Fig. 6

Loss of wnt4 reduces HSPCs numbers and alleviates myeloid hyperplasia in zebrafish. A Sudan Black B (SB) staining of control and wnt4 crispants (wnt4 KO) in both WT and c-myb^hyper larvae at 4 dpf. B Quantification of SB-positive neutrophils in the caudal hematopoietic tissue (CHT) (Student’s t-test; mean ± SD; ****P < 0.0001). C WISH of control and wnt4 crispants (wnt4 KO) in both WT and c-myb^hyper embryos at 60 hpf. D Quantification of c-myb-positive cells in the CHT at 60 hpf (Student’s t-test; mean ± SD; *P < 0.05; ****P < 0.0001). E WISH of control and wnt4 crispants (wnt4 KO) in both WT and c-myb^hyper embryos at 3 dpf. F Quantification of c-myb-positive cells in the CHT at 3 dpf (Student’s t-test; mean ± SD; *P < 0.05; ****P < 0.0001)

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Commun. Signal.