IMAGE

Fig. 4

ID

ZDB-IMAGE-260427-92

Genes

EGFP

Publication

Lardennois et al., 2026 - Two distinct modes of Vgll4-mediated Tead regulation control organ size in zebrafish

All Figures

Figures for Lardennois et al., 2026

Image

Figure Caption

Fig. 4 Vgll4b and Vgll4l are sufficient to rescue the loss of Vgll4 activity in the pLLP, and Vgll4b TDU2 is required for this function.

MIP of confocal Z-stacks showing the pLLP in vgll4b^+/+;vgll4l^+/+ (a), vgll4b^−/−;vgll4l^+/+ (c), vgll4b^−/−;vgll4l^−/− (e) embryos and the same genotypes injected with tRFP-vgll4b mRNA (b, d, f). g Quantification of pLLP cell number in each condition (N ≥ 2 independent replicates). MIP of confocal Z-stacks showing the pLLP in vgll4b^+/+;vgll4l^+/+ (h), and vgll4b^−/−;vgll4l^−/− (i) embryos, injected with vgll4l mRNA at 100 ng/ μL (j, k) or at 200 ng/μL (l, m). n Quantification of pLLP cell number in each condition (N ≥ 2 independent replicates). MIP of confocal Z-stacks showing the pLLP in vgll4b^+/+;vgll4l^+/+ (o), and vgll4b^−/−;vgll4l^−/− (p) embryos, injected with tRFP-vgll4bΔTDU1 (q, r) or tRFP-vgll4bΔTDU2 (s, t) mRNA. u Quantification of pLLP cell number in each condition (N ≥ 3 independent replicates). Data are presented as mean ± SD. Unpaired t-tests (Mann–Whitney) were conducted. Scale bar: 20 μm (a–f, h–m, o–t).

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Commun Biol