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Bastos et al., 2026 - Loss of Cathepsin Z enhances pro-inflammatory macrophage responses and promotes tissue regeneration in zebrafish
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Fig. 2 Under resting conditions, ctsz and nccrp1 are expressed in larval zebrafish macrophages, with very low expression levels of ocstamp in haematopoietic populations. (Ai-iii) Uniform manifold approximation and projections (UMAPs) of the larval haematopoietic/vasculature cluster: nccrp1 in the macrophage cluster within the haematopoietic system (Ai); ocstamp was not detected in the haematopoietic system (Aii); and ctsz expression across development suggests highest expression at ∼4.5 days post-fertilization (dpf) (Aiii). Timeline below UMAPs indicates gene expression across larval development up to 5 dpf.

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