Morpholino

MO2-sirt2

ID

ZDB-MRPHLNO-150911-2

Name

MO2-sirt2

Previous Names

None

Target

Sequence

5' - ACCTCTAAAGGACACAAAAAAGGCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

intron 1 exon 2 splice-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-sirt2

No data available

Phenotype

Phenotype resulting from MO2-sirt2

Phenotype	Fish	Figures
blood island hematopoietic stem cell decreased amount, abnormal	cz3331Tg + MO2-sirt2	Fig. 7 from Morishima et al., 2019
blood island hematopoietic stem cell EGFP expression decreased amount, abnormal	cz3331Tg + MO2-sirt2	Fig. 7 from Morishima et al., 2019
cilium assembly disrupted, abnormal	WT + MO2-sirt2	Fig. S4 from Zhou et al., 2014
Kupffer's vesicle cilium increased length, abnormal	WT + MO2-sirt2	Fig. S4 from Zhou et al., 2014
post-vent region morphology, abnormal	WT + MO2-sirt2	Fig. S7 from Morishima et al., 2019
whole organism gata1a expression decreased amount, abnormal	WT + MO2-sirt2	Fig. 7 from Morishima et al., 2019
whole organism kdrl expression decreased amount, abnormal	WT + MO2-sirt2	Fig. 7 from Morishima et al., 2019
whole organism klf1 expression decreased amount, abnormal	WT + MO2-sirt2	Fig. 7 from Morishima et al., 2019

Phenotype of all Fish created by or utilizing MO2-sirt2

Phenotype	Fish	Conditions	Figures
whole organism gata1a expression decreased amount, abnormal	WT + MO2-sirt2	standard conditions	Fig. 7 from Morishima et al., 2019
post-vent region morphology, abnormal	WT + MO2-sirt2	standard conditions	Fig. S7 from Morishima et al., 2019
cilium assembly disrupted, abnormal	WT + MO2-sirt2	standard conditions	Fig. S4 from Zhou et al., 2014
whole organism klf1 expression decreased amount, abnormal	WT + MO2-sirt2	standard conditions	Fig. 7 from Morishima et al., 2019
Kupffer's vesicle cilium increased length, abnormal	WT + MO2-sirt2	standard conditions	Fig. S4 from Zhou et al., 2014
whole organism kdrl expression decreased amount, abnormal	WT + MO2-sirt2	standard conditions	Fig. 7 from Morishima et al., 2019
blood island hematopoietic stem cell decreased amount, abnormal	cz3331Tg + MO2-sirt2	standard conditions	Fig. 7 from Morishima et al., 2019
blood island hematopoietic stem cell EGFP expression decreased amount, abnormal	cz3331Tg + MO2-sirt2	standard conditions	Fig. 7 from Morishima et al., 2019

Citations