PUBLICATION
Pattern formation in the lateral line of zebrafish
- Authors
- Gompel, N., Cubedo, N., Thisse, C., Thisse, B., Dambly-Chaudiere, C., and Ghysen, A.
- ID
- ZDB-PUB-010705-16
- Date
- 2001
- Source
- Mechanisms of Development 105(1-2): 69-77 (Journal)
- Registered Authors
- Cubedo, Nicolas, Ghysen, Alain, Gompel, Nicolas, Thisse, Bernard, Thisse, Christine
- Keywords
- vertebrates; zebrafish; lateral line; sensory system; peripheral nervous system; migratory primordium; hair cell; neuromasts; pattern formation
- MeSH Terms
-
- Fluorescent Dyes/pharmacology
- Mitosis
- Gene Expression Regulation, Developmental*
- Zebrafish
- Cell Nucleus/metabolism
- Cell Lineage
- Hair Cells, Auditory/metabolism
- Ultraviolet Rays
- Cell Movement
- In Situ Hybridization
- Microscopy, Video
- Neurons/physiology*
- Fluorescein/pharmacology
- Dextrans/pharmacology
- Time Factors
- Animals
- PubMed
- 11429283 Full text @ Mech. Dev.
Citation
Gompel, N., Cubedo, N., Thisse, C., Thisse, B., Dambly-Chaudiere, C., and Ghysen, A. (2001) Pattern formation in the lateral line of zebrafish. Mechanisms of Development. 105(1-2):69-77.
Abstract
The lateral line of fish and amphibians is a sensory system that comprises a number of individual sense organs, the neuromasts, arranged in a defined pattern on the surface of the body. A conspicuous part of the system is a line of organs that extends along each flank (and which gave the system its name). At the end of zebrafish embryogenesis, this line comprises 7-8 neuromasts regularly spaced between the ear and the tip of the tail. The neuromasts are deposited by a migrating primordium that originates from the otic region. Here, we follow the development of this pattern and show that heterogeneities within the migrating primordium prefigure neuromast formation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping