PUBLICATION
Mbx, a novel mouse homeobox gene
- Authors
- Miyamoto, T., Kawahara, A., Teufel, A., Mukhopadhyay, M., Zhao, Y., Dawid, I.B., and Westphal, H.
- ID
- ZDB-PUB-020403-17
- Date
- 2002
- Source
- Development genes and evolution 212(2): 104-106 (Journal)
- Registered Authors
- Dawid, Igor B., Kawahara, Atsuo
- Keywords
- none
- MeSH Terms
-
- Molecular Sequence Data
- Amino Acid Sequence
- Heterogeneous-Nuclear Ribonucleoprotein Group A-B*
- Humans
- Ribonucleoproteins/genetics*
- In Situ Hybridization
- Zebrafish
- Animals
- Brain/embryology
- Genes, Homeobox*
- Mice
- Embryonic and Fetal Development/genetics
- PubMed
- 11914943 Full text @ Dev. Genes Evol.
Citation
Miyamoto, T., Kawahara, A., Teufel, A., Mukhopadhyay, M., Zhao, Y., Dawid, I.B., and Westphal, H. (2002) Mbx, a novel mouse homeobox gene. Development genes and evolution. 212(2):104-106.
Abstract
The homeobox gene Mbxis thought to play important roles in the development of eyes and tectum in zebrafish. We isolated mouse Mbx cDNA and analyzed its expression pattern during early mouse embryogenesis. Expression is predominantly restricted to the midbrain region at E9.5. At subsequent stages of development, Mbx transcripts were also found in the forebrain in addition to midbrain. Thus, the Mbx gene provides a useful molecular marker for early mouse midbrain development and may play a critical role in brain development.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping