PUBLICATION
Muscle differentiation: a gene for slow muscle?
- Authors
- Hughes, S.M.
- ID
- ZDB-PUB-040319-2
- Date
- 2004
- Source
- Current biology : CB 14(4): 156-157 (Journal)
- Registered Authors
- Hughes, Simon M.
- Keywords
- none
- MeSH Terms
-
- Myoblasts, Skeletal/cytology*
- Zebrafish
- Animals
- Transcription Factors/genetics
- Transcription Factors/metabolism*
- Nuclear Proteins
- Muscle Development*
- Hedgehog Proteins
- Gene Expression Regulation
- DNA-Binding Proteins
- Muscle, Skeletal/embryology*
- Cell Differentiation
- Repressor Proteins/genetics
- Repressor Proteins/metabolism*
- Muscle Fibers, Slow-Twitch/metabolism
- Muscle Fibers, Slow-Twitch/physiology*
- Trans-Activators/metabolism
- Zebrafish Proteins
- PubMed
- 15027468 Full text @ Curr. Biol.
Citation
Hughes, S.M. (2004) Muscle differentiation: a gene for slow muscle?. Current biology : CB. 14(4):156-157.
Abstract
Skeletal muscle comes in two fundamental flavours, slow and fast, which determine physiological performance. Zebrafish screens have provided a handle on the molecular mechanism driving slow muscle formation. The transcriptional repressor Blimp1 has now been shown to be required in embryonic slow muscle precursor cells.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping