| ZFIN ID: ZDB-EXP-121213-7 |
Experiment Conditions Description: constant light, chemical treatment: 8-bromo-3',5'-cyclic GMP
| constant light |
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| Name: | constant light |
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| Synonyms: | |
| Definition: | |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000150] |
| chemical treatment: 8-bromo-3',5'-cyclic GMP |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | 8-bromo-3',5'-cyclic GMP |
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| Synonyms: | 8-Br-cGMP, 8-Br-Cyclic GMP, 8-Bromo-cgmp, 8-Bromocyclic GMP, 8-Bromocyclic guanosine monophosphate, 8-bromoguanosine 3',5'-(hydrogen phosphate), 8-Bromoguanosine 3',5'-cyclic monophosphate, 8-Bromoguanosine 3',5'-monophosphate |
| Definition: | A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. |
| Ontology: | ChEBI [CHEBI:64108] ( EBI ) |
| Publication: | Nakao et al., 2012 |
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