| ZFIN ID: ZDB-EXP-171012-13 |
Experiment Conditions Description: chemical treatment by environment: LimKi 3
| chemical treatment by environment: LimKi 3 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | LimKi 3 |
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| Synonyms: | BMS3, LIM Kinase Inhibitor I, N-(5-(1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide, N-{5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-1,3-thiazol-2-yl}-2-methylpropanamide |
| Definition: | A member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2. |
| Ontology: | ChEBI [CHEBI:138670] ( EBI ) |
| Publication: | Dimri et al., 2017 |
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