| ZFIN ID: ZDB-EXP-211028-10 |
Experiment Conditions Description: amputation: caudal fin, chemical treatment: liproxstatin-1
| amputation: caudal fin |
|---|
| Name: | amputation |
|---|---|
| Synonyms: | |
| Definition: | Resection condtion in which all or part of an extremity such as the fin or tail are removed. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000172] |
| Name: | caudal fin |
|---|---|
| Synonyms: | tail, tail fin |
| Definition: | Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines. |
| Ontology: | Anatomy Ontology [ZFA:0001058] |
| chemical treatment: liproxstatin-1 |
|---|
| Name: | chemical treatment |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | liproxstatin-1 |
|---|---|
| Synonyms: | Lip-1, liproxstatin 1, liproxstatin1, N-(3-chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine, N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine |
| Definition: | An azaspiro compound that is 1'H-spiro[piperidine-4,2'-quinoxaline] in which the hydrogen at position 3' is replaced by a (3-chlorobenzyl)amino group. It is a potent inhibitor of ferroptosis. |
| Ontology: | ChEBI [CHEBI:173097] ( EBI ) |
| Publication: | Katikaneni et al., 2020 |
|---|