| ZFIN ID: ZDB-EXP-240618-3 |
Experiment Conditions Description: surgical manipulation: spinal cord, chemical treatment by environment: cimetidine
| surgical manipulation: spinal cord |
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| Name: | surgical manipulation |
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| Synonyms: | |
| Definition: | Experimental condition that involves manual or instrumental techniques to alter anatomical structures. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000176] |
| Name: | spinal cord |
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| Synonyms: | medulla spinalis, spinal cord structure |
| Definition: | |
| Ontology: | Anatomy Ontology [ZFA:0000075] |
| chemical treatment by environment: cimetidine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | cimetidine |
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| Synonyms: | 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine, 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine, Cimetag, cimetidina, cimetidine, cimetidinum, N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidine, Tagamet HB 200, Ulcerfen |
| Definition: | A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach. |
| Ontology: | ChEBI [CHEBI:3699] ( EBI ) |
| Publication: | Oprişoreanu et al., 2023 |
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