ZFIN ID: ZDB-EXP-250723-4
Experiment Conditions Description: heat shock, chemical treatment by environment: metyrapone
heat shock
Name: heat shock
Synonyms:
Definition: Temperature shock condition in which fish are subjected for a short period of time to temperature higher than the controlled temperature. The standard controlled temperature (according to the zebrafish book) is 28.5 degrees C.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000166]
chemical treatment by environment: metyrapone
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: metyrapone
Synonyms: 2-methyl-1,2-dipyridin-3-ylpropan-1-one, metirapona, Metopiron, Metopirone, metyrapone, metyraponum
Definition: An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Ontology: ChEBI [CHEBI:44241]  ( EBI )
Publication: Shvartsburd et al., 2025