| ZFIN ID: ZDB-EXP-250804-15 |
Experiment Conditions Description: chemical treatment by environment: tenofovir (anhydrous)
| chemical treatment by environment: tenofovir (anhydrous) |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | tenofovir (anhydrous) |
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| Synonyms: | (R)-PMPA, ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid, anh. tenofovir, anhydrous tenofovir, tenofovir, tenofovir (anh.) |
| Definition: | A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. |
| Ontology: | ChEBI [CHEBI:63625] ( EBI ) |
| Publication: | Morello et al., 2018 |
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