| ZFIN ID: ZDB-EXP-260520-2 |
Experiment Conditions Description: chemical ablation: gentamycin: kidney, chemical treatment by environment: IWR-1-endo, chemical treatment by environment: IWR-1-exo
| chemical ablation: gentamycin: kidney |
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| Name: | chemical ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses a chemical to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000169] |
| Name: | gentamycin |
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| Synonyms: | 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside, Gentamicin, gentamycins |
| Definition: | Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. |
| Ontology: | ChEBI [CHEBI:17833] ( EBI ) |
| Name: | kidney |
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| Synonyms: | mesonephros |
| Definition: | Cavitated compound organ located in the pleuroperitoneal cavity where hematopoiesis and filtering of blood occur. |
| Ontology: | Anatomy Ontology [ZFA:0000529] |
| chemical treatment by environment: IWR-1-endo |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | IWR-1-endo |
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| Synonyms: | 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide |
| Definition: | A dicarboximide having an endo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. |
| Ontology: | ChEBI [CHEBI:62882] ( EBI ) |
| chemical treatment by environment: IWR-1-exo |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | IWR-1-exo |
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| Synonyms: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide |
| Definition: | A dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo. |
| Ontology: | ChEBI [CHEBI:62883] ( EBI ) |
| Publication: | Kamei et al., 2026 |
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