| ZFIN ID: ZDB-EXP-260520-5 |
Experiment Conditions Description: chemical ablation: gentamycin: kidney, chemical treatment by environment: PP2
| chemical ablation: gentamycin: kidney |
|---|
| Name: | chemical ablation |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition which uses a chemical to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000169] |
| Name: | gentamycin |
|---|---|
| Synonyms: | 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside, Gentamicin, gentamycins |
| Definition: | Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. |
| Ontology: | ChEBI [CHEBI:17833] ( EBI ) |
| Name: | kidney |
|---|---|
| Synonyms: | mesonephros |
| Definition: | Cavitated compound organ located in the pleuroperitoneal cavity where hematopoiesis and filtering of blood occur. |
| Ontology: | Anatomy Ontology [ZFA:0000529] |
| chemical treatment by environment: PP2 |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | PP2 |
|---|---|
| Synonyms: | 1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, AG 1879, AG-1879, AG1879 |
| Definition: | A member of the class of pyrazolopyrimidine that is pyrazolo[3,4-d]pyrimidin-4-amine bearing additional tert-butyl and 4-chlorophenyl substituents at positions 1 and 3 respectively. It is a potent ATP-competitive inhibitor of the Src family of protein tyrosine kinases. |
| Ontology: | ChEBI [CHEBI:78331] ( EBI ) |
| Publication: | Kamei et al., 2026 |
|---|