| ZFIN ID: ZDB-EXP-260520-7 |
Experiment Conditions Description: chemical ablation: gentamycin: kidney, chemical treatment by environment: Y-27632
| chemical ablation: gentamycin: kidney |
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| Name: | chemical ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses a chemical to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000169] |
| Name: | gentamycin |
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| Synonyms: | 4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside, Gentamicin, gentamycins |
| Definition: | Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. |
| Ontology: | ChEBI [CHEBI:17833] ( EBI ) |
| Name: | kidney |
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| Synonyms: | mesonephros |
| Definition: | Cavitated compound organ located in the pleuroperitoneal cavity where hematopoiesis and filtering of blood occur. |
| Ontology: | Anatomy Ontology [ZFA:0000529] |
| chemical treatment by environment: Y-27632 |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | Y-27632 |
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| Synonyms: | (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide, trans-4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide, Y 27632 |
| Definition: | A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme. |
| Ontology: | ChEBI [CHEBI:75393] ( EBI ) |
| Publication: | Kamei et al., 2026 |
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