Publication	Data		Fish	Anatomy
Guner-Ataman et al., 2018	Fig. 1		tbx1tu285/tu285 ,   tbx1tu285/tu285; la116Tg	adductor hyomandibulae absent, abnormal adductor mandibulae absent, abnormal adductor operculi absent, abnormal bulbus arteriosus absent, abnormal dilatator operculi absent, abnormal hyohyoideus absent, abnormal interhyoideus absent, abnormal levator arcus palatini absent, abnormal levator operculi absent, abnormal pharyngeal arch angioblastic mesenchymal cell absent, abnormal pharyngeal arch artery absent, abnormal pharyngeal arch artery morphology, abnormal pharyngeal arch has fewer parts of type angioblastic mesenchymal cell, abnormal ventral intermandibularis anterior absent, abnormal ventral intermandibularis posterior absent, abnormal
	Fig. 2		tbx1tu285/tu285; fb7Tg ,   tbx1tu285/tu285	pharyngeal arch 2 absent, abnormal pharyngeal arch 3 absent, abnormal pharyngeal arch 4 absent, abnormal pharyngeal arch absent, abnormal
	Fig. 3		tbx1tu285/tu285	anterior lateral plate mesoderm nkx2.5 expression absent, abnormal anterior lateral plate mesoderm nkx2.5 expression decreased amount, abnormal anterior lateral plate mesoderm nkx2.5 expression decreased distribution, abnormal
	Fig. 5		tbx1tu285/tu285	anterior lateral plate mesoderm gdf3 expression decreased amount, abnormal anterior lateral plate mesoderm gdf3 expression decreased distribution, abnormal
	Fig. S5		tbx1tu285/tu285	anterior lateral plate mesoderm nkx2.5 expression absent, abnormal
Choe et al., 2014	Fig. 1		tbx1tu285/tu285; el72Tg; pt6Tg ,   tbx1tu285/tu285; el72Tg	pharyngeal pouch malformed, abnormal pharyngeal pouch pharyngeal system development process quality, abnormal pharyngeal system development process quality, abnormal
	Fig. 2		tbx1tu285/tu285 ,   tbx1tu285/tu285; ne1911Tg	ceratobranchial cartilage absent, abnormal pharyngeal arch cartilage malformed, abnormal pharyngeal pouch absent, abnormal pharyngeal pouch malformed, abnormal pharyngeal pouch pharyngeal system development process quality, abnormal pharyngeal system development process quality, abnormal
	Fig. 3		tbx1tu285/tu285	ceratobranchial cartilage absent, abnormal pharyngeal arch cartilage malformed, abnormal pharyngeal pouch decreased amount, abnormal
Choudhry et al., 2013	Fig. 1		tbx1tm208/tm208	atrium decreased angle to cardiac ventricle, abnormal atrium increased width, abnormal cardiac ventricle increased width, abnormal heart jogging disrupted, abnormal heart looping disrupted, abnormal heart straight, abnormal
	Fig. 2		tbx1tm208/tm208	cardiac muscle cell circular, abnormal cardiac muscle cell shape, abnormal
	Fig. 4		tbx1tm208/tm208	bulbus arteriosus decreased length, abnormal bulbus arteriosus immature, abnormal bulbus arteriosus smooth muscle morphology, abnormal
	Fig. S1		tbx1tm208/tm208	atrium increased width, abnormal cardiac ventricle increased width, abnormal cardiac ventricle shortened, abnormal
	Fig. S2		tbx1tm208/tm208; twu34Tg	cardiac muscle cell decreased amount, abnormal cell population proliferation decreased rate, abnormal
	Fig. S4		tbx1tm208/tm208	heart contraction decreased rate, abnormal heart decreased functionality, abnormal
Nevis et al., 2013	Fig. 2		tbx1tu285/tu285; f2Tg ,   tbx1tu285/tu285; fb7Tg	cardiac ventricle decreased size, abnormal cardiac ventricle has fewer parts of type cardiac muscle cell, abnormal
	Fig. 5		tbx1tu285/tu285; fb7Tg	heart primordium cell population proliferation decreased process quality, abnormal
Wang et al., 2013	Fig. 1		WT + MO3-tbx1	neural crest cell decreased amount, abnormal
Zhang et al., 2010	Fig. 1		AB + MO2-tbx1	aortic arch decreased amount, abnormal macula hypoplastic, abnormal otic vesicle decreased size, abnormal semicircular canal hypoplastic, abnormal thymus aplastic, abnormal thymus hypoplastic, abnormal
	Fig. 2		AB + MO2-tbx1	ceratobranchial cartilage aplastic, abnormal hindbrain neural crest cell decreased amount, abnormal Meckel's cartilage decreased size, abnormal midbrain neural crest cell decreased amount, abnormal pharyngeal arch 2 skeleton decreased size, abnormal pharyngeal arch 3-7 neural crest cell absent, abnormal
	Fig. 3		AB + MO2-tbx1	pharyngeal arch 1 neural crest cell decreased amount, abnormal pharyngeal arch 1 neural crest cell present, abnormal pharyngeal arch 2 neural crest cell absent, abnormal pharyngeal arch 2 neural crest cell decreased amount, abnormal pharyngeal arch 3-7 neural crest cell absent, abnormal
	Fig. 4		AB + MO2-tbx1	heart contraction decreased rate, abnormal heart decreased contractility, abnormal
	Fig. 5		AB + MO2-tbx1	atrium decreased size, abnormal blood circulation disrupted, abnormal cardiac ventricle decreased size, abnormal heart development disrupted, abnormal heart looping disrupted, abnormal heart symmetry, abnormal
Lin et al., 2009	Fig. 6		twu3Tg + MO1-tbx1	pharyngeal arch muscle aplastic, abnormal
Knight et al., 2008	Fig. 5		tbx1tm208/tm208	chordate pharyngeal muscle development disrupted, abnormal constrictor dorsalis morphology, abnormal
Phenotype Annotation (1994-2006)	Fig. for (tm208)		tbx1tm208/tm208	anatomical system quality, abnormal inner ear quality, abnormal mouth quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal sensory system quality, abnormal whole organism lethal (sensu genetics), abnormal
	Fig. for (tu285)		tbx1tu285/tu285	anatomical system quality, abnormal brain quality, abnormal inner ear quality, abnormal midbrain quality, abnormal nervous system quality, abnormal palatoquadrate arch quality, abnormal sensory system quality, abnormal whole organism lethal (sensu genetics), abnormal
Holzschuh et al., 2005	Fig. 3		tbx1tm208/tm208	endoderm development disrupted, abnormal epibranchial ganglion fused with epibranchial ganglion, abnormal epibranchial ganglion increased size, abnormal glossopharyngeal ganglion absent, abnormal pharyngeal pouch aplastic, abnormal pharyngeal pouch malformed, abnormal
Piotrowski et al., 2000	Fig. 11		tbx1tu285/tu285 ,   tbx1tm208/tm208	pharynx malformed, abnormal
	Fig. 12		tbx1tu285/tu285 ,   tbx1tm208/tm208	digestive system development disrupted, abnormal mesenchyme decreased size, abnormal notochord mislocalised anteriorly, abnormal pharynx development hypotrophic growth, abnormal pharynx malformed, abnormal
	Fig. 13		tbx1tu285/tu285 ,   tbx1tm208/tm208	dilatator operculi aplastic, abnormal levator arcus palatini aplastic, abnormal ventral transverse aplastic, abnormal
	Fig. 2		tbx1tu285/tu285 ,   tbx1tm208/tm208	cartilage morphogenesis disrupted, abnormal mouth mislocalised posteriorly, abnormal otic vesicle decreased size, abnormal parachordal cartilage malformed, abnormal pharyngeal arch 3-7 skeleton decreased size, abnormal pharyngeal arch cartilage decreased size, abnormal pharyngeal arch cartilage fused with pharyngeal arch cartilage, abnormal semicircular canal aplastic, abnormal
	Fig. 3		tbx1tu285/tu285 ,   tbx1tm208/tm208	anterior crista primordium aplastic, abnormal aortic arch decreased amount, abnormal lateral crista primordium aplastic, abnormal posterior crista primordium aplastic, abnormal
	Fig. 4		tbx1tu285/tu285 ,   tbx1tm208/tm208	mouth closure incomplete, abnormal mouth mislocalised posteriorly, abnormal pharyngeal arch aplastic, abnormal
	Fig. 6		tbx1tu285/tu285 ,   tbx1tm208/tm208	inner ear decreased size, abnormal pharyngeal arch cartilage disorganized, abnormal
	Fig. 7		tbx1tu285/tu285 ,   tbx1tm208/tm208	pharyngeal arch cartilage fused with pharyngeal arch cartilage, abnormal pharyngeal pouch aplastic, abnormal
	Fig. 8		tbx1tu285/tu285 ,   tbx1tm208/tm208	cartilage morphogenesis disrupted, abnormal pharyngeal arch 3-7 neural crest cell fused with pharyngeal arch 3-7 neural crest cell, abnormal pharyngeal pouch aplastic, abnormal
	Fig. 9		tbx1tu285/tu285 ,   tbx1tm208/tm208	pharyngeal arch 3-7 morphology, abnormal pharyngeal pouch aplastic, abnormal pharyngeal pouch decreased amount, abnormal thymus aplastic, abnormal
	text only		tbx1tu285/tu285 ,   tbx1tm208/tm208	pericardium edematous, abnormal swim bladder non-functional, abnormal whole organism viability, abnormal
Piotrowski et al., 1996	Fig. 5		tbx1tm208/tm208	auditory capsule decreased size, abnormal auditory capsule malformed, abnormal ceratobranchial cartilage decreased size, abnormal ceratohyal cartilage morphology, abnormal Meckel's cartilage inverted, abnormal Meckel's cartilage mislocalised posteriorly, abnormal Meckel's cartilage mislocalised ventrally, abnormal palatoquadrate cartilage decreased size, abnormal parachordal cartilage mislocalised posteriorly, abnormal
	text only		tbx1tu285/tu285	auditory capsule decreased size, abnormal auditory capsule malformed, abnormal ceratobranchial cartilage decreased size, abnormal ceratohyal cartilage morphology, abnormal Meckel's cartilage inverted, abnormal Meckel's cartilage mislocalised posteriorly, abnormal Meckel's cartilage mislocalised ventrally, abnormal midbrain morphology, abnormal palatoquadrate cartilage decreased size, abnormal parachordal cartilage mislocalised posteriorly, abnormal
Whitfield et al., 1996	Fig. 2		tbx1tu285/tu285 ,   tbx1tm208/tm208	inner ear decreased size, abnormal inner ear structure, abnormal otic vesicle decreased size, abnormal semicircular canal aplastic, abnormal
	Fig. 3		tbx1tu285/tu285 ,   tbx1tm208/tm208	macula decreased amount, abnormal
	Fig. 4		tbx1tu285/tu285 ,   tbx1tm208/tm208	anterior crista primordium aplastic, abnormal lateral crista primordium aplastic, abnormal posterior crista primordium aplastic, abnormal semicircular canal morphogenesis arrested, abnormal
	Table 2		tbx1tu285/tu285 ,   tbx1tm208/tm208	mandibular arch skeleton morphology, abnormal whole organism circling, abnormal whole organism movement behavioral quality, abnormal whole organism viability, abnormal