Term Name: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Synonyms: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide, D237, histone deacetylase inhibitor III, M-344, M344, N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
Definition: A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.
Ontology: ChEBI [CHEBI:125562]  ( EBI )

Relationships
is a type of: benzamides hydroxamic acid secondary carboxamide tertiary amino compound
has_role: antineoplastic agent apoptosis inducer EC 3.5.1.98 (histone deacetylase) inhibitor