Term Name: 6beta-hydroxycortisone
Synonyms: 6beta,17,21-trihydroxypregn-4-ene-3,11,20-trione, 6beta-17alpha,21-trihydroxypregn-4-ene-3,11,20-trione, 6beta-hydroxycortisone
Definition: A C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo.
Ontology: ChEBI [CHEBI:139269]  ( EBI )

Relationships
is a type of: 3-oxo-Delta(4) steroid 6beta-hydroxy steroid 11-oxo steroid 17alpha-hydroxy steroid 20-oxo steroid 21-hydroxy steroid C21-steroid primary alpha-hydroxy ketone tertiary alpha-hydroxy ketone
has_functional_parent: cortisone
has_role: human metabolite probe