Term Name:	SHP099
Synonyms:	6-(4-amino-4-methyl-1-piperidinyl)-3-(2,3-dichlorophenyl)-2-pyrazinamine, 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine, SHP 099, SHP-099
Definition:	A member of the class of pyrazines that is pyrazine substituted by amino, 2,3-dichlorophenyl, and 4-amino-4-methylpiperidin-1-yl groups at positions 2, 3, and 6, respectively. It is an allosteric SHP2 inhibitor, with IC50s of 0.690, 1.241, 0.416, 1.968, and 2.896 muM for SHP2, SHP2(D61Y), SHP2(E69K), SHP2(A72V), and SHP2(E76K).
Ontology:	ChEBI [CHEBI:234265]  ( EBI )