Term Name: manumycin A
Synonyms: (-)-manumycin A, (2E,4E,6R)-N-[(1S,5S,6R)-5-Hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-2,4-decadienamide, (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyldeca-2,4-dienamide, manumycin, manumycin A, NSC 622141, UCF 1C, UCF1-C
Definition: A polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties.
Ontology: ChEBI [CHEBI:29623]  ( EBI )

Relationships
is a type of: enamide epoxide organic heterobicyclic compound polyketide secondary carboxamide tertiary alcohol
has_role: antiatherosclerotic agent antimicrobial agent antineoplastic agent apoptosis inducer bacterial metabolite EC 1.8.1.9 (thioredoxin reductase) inhibitor EC 2.5.1.58 (protein farnesyltransferase) inhibitor marine metabolite