Term Name: naloxone
Synonyms: (-)-naloxone, 1-N-Allyl-14-hydroxynordihydromorphinone, 17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one, 3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one, naloxona, naloxone, naloxonum
Definition: A synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose.
Ontology: ChEBI [CHEBI:7459]  ( EBI )

Relationships
is a type of: morphinane alkaloid organic heteropentacyclic compound tertiary alcohol
has_parent_hydride: morphinan
has_role: antidote to opioid poisoning central nervous system depressant mu-opioid receptor antagonist
inverse has_functional_parent: naloxegol
inverse is_conjugate_acid_of: naloxone(1+)
is_conjugate_base_of: naloxone(1+)