Term Name: rac-crizotinib
Synonyms: (+-)-crizotinib, (RS)-crizotinib, rac-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine, racemic crizotinib
Definition: A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer.
Ontology: ChEBI [CHEBI:77563]  ( EBI )

Relationships
is a type of: racemate
has_part: crizotinib ent-crizotinib
has_role: antineoplastic agent biomarker EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor