Term Name: MDL-28170
Synonyms: benzyl [(2S)-3-methyl-1-oxo-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]amino}butan-2-yl]carbamate, calpain inhibitor III, carbobenzoxyvalylphenylalanine aldehyde, Cbz-Val-Phe-H, CbzValPheH, L-benzyloxycarbonyl-L-valyl-L-phenylalaninal, MDL 28,170, MDL 28170, MDL-28170, MDL28170, N-benzyloxycarbonyl-L-valyl-L-phenylalaninal, N-benzyloxycarbonylvalylphenylalaninal, N-benzyloxycarbonylvalylphenylalanine aldehyde, N-CBZ-Val-Phe-al, Z-Val-Phe-al, Z-Val-Phe-CHO, Z-Val-Phe-H
Definition: A dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor.
Ontology: ChEBI [CHEBI:82818]  ( EBI )

Relationships
is a type of: aldehyde carbamate ester secondary carboxamide
has_role: anticoronaviral agent antileishmanial agent apoptosis inhibitor EC 3.4.22.52 (calpain-1) inhibitor EC 3.4.22.53 (calpain-2) inhibitor EC 3.4.23.46 (memapsin 2) inhibitor