| Term Name: | marginal zone B cell |
|---|---|
| Synonyms: | marginal zone B lymphocyte, marginal zone B-cell, marginal zone B-lymphocyte, MZ B cell, MZ B lymphocyte, MZ B-cell, MZ B-lymphocyte |
| Definition: | A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. |
| Ontology: | Cell Ontology [CL:0000845] |