Term Name: CD3gamma deficiency
Synonyms:
Definition: A severe combined immunodeficiency that has_material_basis_in autosomal recessive mutations in the gene coding for T-cell surface glycoprotein CD3gamma chain precursors. Patients with CD3gamma deficiency have a severe defect in the expression of the T-cell receptor CD3-complex. Affected patients have decreased T-cell numbers and function; B cells are variably affected.
Ontology: Human Disease [DOID:0060018]   ( DOID:0060018 )

Relationships
is a type of: autosomal recessive disease severe combined immunodeficiency