Term Name:	type I complement component 8 deficiency
Synonyms:
Definition:	A complement deficiency that is characterized by deficiency of the alpha subunit of complement protein 8, which causes increased susceptibility to recurrent bacterial infections, especially to Neisseria meningitidis, and has_material_basis_in autosomal recessive inheritance of mutation in the C8A gene, which produces the alpha subunit of complement component 8 important in forming membrane attack complexes.
Ontology:	Human Disease [DOID:0060301]   ( DOID:0060301 )