Term Name:	holoprosencephaly 12
Synonyms:	holoprosencephaly-12 with or without pancreatic agenesis
Definition:	A holoprosencephaly that is characterized by abnormal separation of the embryonic forebrain resulting in dysmorphic facial features and often, but not always, impaired neurologic development and that has_material_basis_in heterozygous mutation in the CNOT1 gene on chromosome 16q21.
Ontology:	Human Disease [DOID:0081398]   ( DOID:0081398 )