Term Name:	immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia
Synonyms:	IMD73B
Definition:	A combined immunodeficiency characterized by onset of recurrent infections in infancy or early childhood and variable immune system abnormalities including B- and T-cell lymphopenia, decreased immunoglobulin subsets, decreased TCR excision circles and dysfunctional T cells, decreased NK cells, neutropenia, and impaired neutrophil chemotaxis that has_material_basis_in heterozygous gain-of-function mutation in the RAC2 gene on chromosome 22q13.1.
Ontology:	Human Disease [DOID:0112061]   ( DOID:0112061 )