Term Name: pyroptotic inflammatory response
Synonyms: pyroptosis
Definition: A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death.
Ontology: GO: Biological Process [GO:0070269]    QuickGO    AmiGO

Relationships
is a type of: inflammatory response
has subtype: pyroptotic cell death
negatively regulated by: negative regulation of pyroptotic inflammatory response
positively regulated by: positive regulation of pyroptotic inflammatory response