Term Name:	apical ectodermal ridge
Synonyms:	AER, apical epidermal ridge, crista ectodermalis apicalis
Definition:	multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP].
Ontology:	Cell Ontology [UBERON:0004356]