Search Ontology:
ChEBI
grazoprevir
- Term ID
- CHEBI:132975
- Synonyms
-
- (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]qui
- grazoprevir
- MK 5172
- Definition
- An azamacrocyclic compound that is a hepatitis C protease inhibitor used in combination with elbasvir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults.
- References
-
- cas:1350514-68-9
- drugcentral:5081
- pmc:PMC4135988
- pubmed:24666106
- pubmed:24727022
- pubmed:25266288
- pubmed:25467560
- pubmed:25467591
- pubmed:26353843
- pubmed:26423374
- pubmed:26532861
- pubmed:26682473
- pubmed:26818134
- pubmed:26849059
- pubmed:26926625
- pubmed:26933896
- pubmed:26938699
- pubmed:26943930
- pubmed:27091555
- pubmed:27123552
- pubmed:27291249
- pubmed:27403342
- pubmed:27418810
- reaxys:19999739
- wikipedia.en:Grazoprevir
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from grazoprevir
Phenotype where environments contain grazoprevir
Phenotype modified by environments containing grazoprevir
Phenotype affecting grazoprevir
Human Disease Model