naltrexone hydrochloride

Term ID

CHEBI:134687

Synonyms

(5alpha,17R)-17-(cyclopropylmethyl)-3,14-dihydroxy-6-oxo-4,5-epoxymorphinan-17-ium chloride
17-(cyclopropylmethyl)-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one hydrochloride
17-(Cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-one hydrochloride
N-Cyclopropylmethyl-noroxymorphone hydrochloride
naltrexone monohydrochloride
naltrexone.HCl

Definition

A hydrochloride obtained by reaction of oxycodone with one molar equivalent of hydrochloric acid. it is a μ-opioid receptor antagonist that is used to treat alcohol dependence.

References

cas:16676-29-2
drugbank:DB00704
kegg.drug:D02095
pubmed:20949341
pubmed:22528547
pubmed:22595640
pubmed:22616317
pubmed:22759074
pubmed:22941847
pubmed:23227366
pubmed:23745947
pubmed:24090623
pubmed:24234803
pubmed:25445974
pubmed:25655411
pubmed:26185466
pubmed:26309861
pubmed:26695349
pubmed:26773883
pubmed:27137146
pubmed:27211522
pubmed:27440072
pubmed:27525968
pubmed:27627782
reaxys:3580333
wikipedia.en:Naltrexone

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from naltrexone hydrochloride

Phenotype where environments contain naltrexone hydrochloride

Phenotype modified by environments containing naltrexone hydrochloride

Phenotype affecting naltrexone hydrochloride

Human Disease Model