Search Ontology:
ChEBI
camostat
- Term ID
- CHEBI:135632
- Synonyms
-
- 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
- 4-{2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl}phenyl 4-carbamimidamidobenzoate
- camostat
- camostat mesilate
- camostatum
- N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
- Definition
- A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients.
- References
-
- cas:59721-28-7
- chemspider:2440
- drugbank:DB13729
- drugcentral:471
- kegg.drug:D07606
- pmc:PMC7809394
- pubmed:23412700
- pubmed:26166259
- pubmed:26887332
- pubmed:33176395
- pubmed:33225308
- pubmed:33505639
- pubmed:33564221
- pubmed:33676899
- pubmed:7341342
- wikipedia.en:Camostat
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from camostat
Phenotype where environments contain camostat
Phenotype modified by environments containing camostat
Phenotype affecting camostat
Human Disease Model