spirapril

Term ID

CHEBI:135756

Synonyms

• (8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid

Definition

An azaspiro compound resulting from the formal condensation of the amino group of (8S)-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid with the carboxy group of N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanine. It is a prodrug for the antihypertensive drug spiraprilat.

References

• cas:83647-97-6
• drugbank:DB01348
• drugcentral:2474
• hmdb:HMDB0015438
• kegg.drug:D08529
• pubmed:10499560
• pubmed:10499561
• pubmed:12613273
• pubmed:8638865
• pubmed:9345854
• reaxys:4277924
• wikipedia.en:Spirapril

Ontology

ChEBI  ( EBI )

Resources

CTD