cabotegravir

Term ID

CHEBI:172944

Synonyms

(3S,11aR)-N-(2,4-difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide
CAB
cabotegravir
cabotegravirum
GSK 1265744
GSK 744
GSK-1265744
GSK-1265744A
GSK1265744
GSK1265744A
GSK744
GSK744 LA
GSK744 LAP
S-265744
S/GSK1265744

Definition

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (3S,11aR)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1.

References

cas:1051375-10-0
chemspider:30829503
drugbank:DB11751
kegg.drug:D10548
pmc:PMC7776404
pubmed:24144896
pubmed:24594934
pubmed:25469523
pubmed:25589630
pubmed:25589631
pubmed:29410019
pubmed:29746267
pubmed:31644481
pubmed:32164474
pubmed:32341511
pubmed:32361755
pubmed:32447500
pubmed:32495274
pubmed:32497490
pubmed:32592669
pubmed:32882042
pubmed:33005698
pubmed:33112699
pubmed:33136751
pubmed:33148996
pubmed:33289810
pubmed:33308425
pubmed:33347943
pubmed:33593093
pubmed:33730748
pubmed:33770512
pubmed:33770513
pubmed:33794181
pubmed:33821887
pubmed:33822851
pubmed:33830459
pubmed:33872258
pubmed:33957367
wikipedia.en:Cabotegravir

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from cabotegravir

Phenotype where environments contain cabotegravir

Phenotype modified by environments containing cabotegravir

Phenotype affecting cabotegravir

Human Disease Model