goralatide

Term ID

CHEBI:191178

Synonyms

(2S)-1-[(2S)-2-{[(2S)-2-{[(2S)-2-acetamido-3-hydroxypropanoyl]amino}-3-carboxypropanoyl]amino}-6-aminohexanoyl]pyrrolidine-2-carboxylic acid
Ac-L-Ser-L-Asp-L-Lys-L-Pro
Ac-SDKP
Ac-Ser-Asp-Lys-Pro
Ac-Ser-Asp-Lys-Pro-OH
acetyl-N-Ser-Asp-Lys-Pro
acetyl-seryl-aspartyl-lysyl-proline
AcSDKP
goralatida
goralatide
goralatidum
N-acetyl-L-Ser-L-Asp-L-Lys-L-Pro
N-acetyl-L-seryl-L-alpha-aspartyl-L-lysyl-L-proline
N-acetyl-Ser-Asp-Lys-Pro
N-acetyl-seryl-aspartyl-lysyl-proline
NAcSerAspLysPro
seraspenide

Definition

A tetrapeptide that is Ser-Asp-Lys-Pro in which the N-terminal amino group carries an acetyl group. It is selective inhibitor of primitive haematopoietic cell proliferation and exhibits anti-inflammatory, anti-fibrotic, and pro-angiogenic properties.

References

cas:120081-14-3
chemspider:59343
hmdb:HMDB0062552
pubmed:15256375
pubmed:23351021
pubmed:23833979
pubmed:25331328
pubmed:26048023
pubmed:26324505
pubmed:26350537
pubmed:26656271
pubmed:27425816
pubmed:27577858
pubmed:28075040
pubmed:28164637
pubmed:28245754
pubmed:28771231
pubmed:2915977
pubmed:29269295
pubmed:29620193
pubmed:29684394
pubmed:29722788
pubmed:29990624
pubmed:30403163
pubmed:30826375
pubmed:30900390
pubmed:30949886
pubmed:30972974
pubmed:30998852
pubmed:31290182
pubmed:31387512
pubmed:31997585
pubmed:32352559
pubmed:32435194
pubmed:33135306
pubmed:33694311
pubmed:33948088
pubmed:34347311
pubmed:34508023
pubmed:34576239
pubmed:34608942
pubmed:34921949
pubmed:35101843
pubmed:35255573
pubmed:35750251

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from goralatide

Phenotype where environments contain goralatide

Phenotype modified by environments containing goralatide

Phenotype affecting goralatide

Human Disease Model