BMY-25067

Term ID

CHEBI:195316

Synonyms

[(1aS,8S,8aR,8bS)-8a-methoxy-5-methyl-6-({2-[(4-nitrophenyl)disulfanyl]ethyl}amino)-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
BMS 181174
BMS-181174
BMS181174
BMY 25067
BMY25067
N-7-(2-(nitrophenyldithio)ethyl)mitomycin C

Definition

An organic disulfide that is mitomycin C in which the amino group at position 7 is replaced by a {2-[(4-nitrophenyl)disulfanyl]ethyl}amino group. It is a derivative of mitomycin C with activity against a range of tumour cell lines and xenografts.

References

cas:95056-36-3
patent:US5703111
pubmed:10072677
pubmed:10587292
pubmed:1423311
pubmed:15053618
pubmed:15678185
pubmed:16765324
pubmed:1688200
pubmed:2125529
pubmed:2153443
pubmed:2380013
pubmed:2550081
pubmed:2767361
pubmed:3440251
pubmed:7488240
pubmed:7656243
pubmed:8297721
pubmed:8517871
pubmed:8735495
pubmed:8758917
pubmed:9090717
pubmed:9113102
pubmed:9275022
pubmed:9535170
pubmed:9667686
pubmed:9815817

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from BMY-25067

Phenotype where environments contain BMY-25067

Phenotype modified by environments containing BMY-25067

Phenotype affecting BMY-25067

Human Disease Model