MCC950

Term ID

CHEBI:231684

Synonyms

CP-456,773
CP-456773
CRID3
cytokine release inhibitory drug 3
MCC 950
MCC-950
N-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl)-4-(2-hydroxypropan-2-yl)furan-2-sulfonamide

Definition

A member of the class of s-indacenes that is 1,2,3,5,6,7-hexahydro-s-indacene substituted by a ({[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonyl}carbamoyl)amino group at position 4. It is a potent and selective NLRP3 inhibitor.

References

cas:210826-40-7
pubmed:32956781
pubmed:35579347
pubmed:36562558
pubmed:36562561
pubmed:37150865
pubmed:37515181
pubmed:37591025
pubmed:37602308
pubmed:37702910
pubmed:37858713
pubmed:37958819
pubmed:38039716
pubmed:38040385
pubmed:38114914
pubmed:38240215
pubmed:38269433
pubmed:38319525
pubmed:38338456
pubmed:38340397
pubmed:38460298
pubmed:38509779
pubmed:38519142
pubmed:38692345
pubmed:38752538
pubmed:38797898
pubmed:38902941
pubmed:39003648
pubmed:39121559
pubmed:39180246
pubmed:39183455
pubmed:39217887

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from MCC950

Phenotype where environments contain MCC950

Phenotype modified by environments containing MCC950

Phenotype affecting MCC950

Human Disease Model