digitonin

Term ID

CHEBI:27729

Synonyms

(25R)-2alpha,15beta-dihydroxy-5alpha-spirostan-3beta-yl beta-D-glucopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->3)]-beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranoside
Digitin
Digitonin

Definition

A spirostanyl glycoside that is digitogenin in which the 3-hydroxy group is substituted by a β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-glucopyranosyl-(1→4)-β-D-galactopyranosyl group. It is a steroidal saponin isolated from the foxglove plant, Digitalis purpurea. It is used extensively as a mild non-ionic detergent for extracting proteins from membranes for structure and function studies.

References

beilstein:78654
cas:11024-24-1
chemspider:4976216
kegg.compound:C00765
knapsack:C00003574
lipidmaps:LMST01080003
metacyc.compound:CPD0-1629
patent:CN101829228
pubmed:11603432
pubmed:19049416
pubmed:20072627
pubmed:21752631
pubmed:21951169
pubmed:22480420
pubmed:23062361
pubmed:23146422
pubmed:25412206
pubmed:25555589
pubmed:26349826
pubmed:26569199
pubmed:27147060
pubmed:27518122
pubmed:28333465
pubmed:28551523
pubmed:30240438
pubmed:32280324
pubmed:33333059
pubmed:33428933
pubmed:34330992
pubmed:34351328
wikipedia.en:Digitonin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from digitonin

Phenotype where environments contain digitonin

Phenotype modified by environments containing digitonin

Phenotype affecting digitonin

Human Disease Model