vancomycin

Term ID

CHEBI:28001

Synonyms

(1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21
(2.2Sp,3.5Sa,2.6Sp)-O(4.2),C(3.4):C(5.4),O(4.6):C(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-
(3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methy
Vancocin
vancomicin
vancomicina
Vancomycin
vancomycine
vancomycinum

Definition

A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.

References

cas:1404-90-6
drugbank:DB00512
drugcentral:2807
kegg.compound:C06689
kegg.drug:D00212
knapsack:C00016052
metacyc.compound:CPD-12245
patent:US3067099
pdb-ccd:VAN
pubmed:11028184
pubmed:11408222
pubmed:11688538
pubmed:11864951
pubmed:11886013
pubmed:11980329
pubmed:12019070
pubmed:12541895
pubmed:12852813
pubmed:13370625
pubmed:13521912
pubmed:14605050
pubmed:14702667
pubmed:15047516
pubmed:15081082
pubmed:15465645
pubmed:15590714
pubmed:15792257
pubmed:16183423
pubmed:16184232
pubmed:16420976
pubmed:16596002
pubmed:16720708
pubmed:17027219
pubmed:17184835
pubmed:17299012
pubmed:17594206
pubmed:18030187
pubmed:18159039
pubmed:18162343
pubmed:18260149
pubmed:18361944
pubmed:18462092
pubmed:18582342
pubmed:18817166
pubmed:18983037
pubmed:19107100
pubmed:19830166
pubmed:20956604
pubmed:21109901
pubmed:21458937
pubmed:21466775
pubmed:21664803
pubmed:21719238
pubmed:21951032
pubmed:22011388
pubmed:22015328
pubmed:22027450
pubmed:22124537
reaxys:3132
wikipedia.en:Vancomycin

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from vancomycin

Phenotype where environments contain vancomycin

Phenotype modified by environments containing vancomycin

Phenotype affecting vancomycin

Human Disease Model