emtricitabine

Term ID

CHEBI:31536

Synonyms

• (-)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
• (-)-2'-deoxy-5-fluoro-3'-thiacytidine
• (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine
• (-)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
• (-)-FTC
• (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
• 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
• 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one
• 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
• EMTRICITABINE

Definition

An organofluorine compound that is 5-fluorocytosine substituted at the 1 position by a 2-(hydroxymethyl)-1,3-oxathiolan-5-yl group (2R,5S configuration). It is used in combination therapy for the treatment of HIV-1 infection.

References

• beilstein:5908714
• cas:143491-57-0
• drugbank:DB00879
• drugcentral:1003
• kegg.compound:C12599
• kegg.drug:D01199
• patent:US5538975
• patent:WO9214743
• pdb-ccd:ETV
• pubmed:11491420
• pubmed:14609348
• pubmed:14693538
• pubmed:15206508
• pubmed:15249567
• pubmed:15588339
• pubmed:15875341
• pubmed:15977972
• pubmed:16034488
• pubmed:16323102
• pubmed:16401810
• pubmed:17526857
• pubmed:19493710
• pubmed:22915463
• pubmed:22917277
• pubmed:22935078
• pubmed:23337366
• pubmed:23361642
• pubmed:25017682
• wikipedia.en:Emtricitabine

Ontology

ChEBI  ( EBI )

Resources

CTD