pentamidine

Term ID

CHEBI:45081

Synonyms

1,5-bis(4-amidinophenoxy)pentane
4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide
4,4'-(pentamethylenedioxy)dibenzamidine
4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
4,4'-Diamidinodiphenoxypentane
p,p'-(pentamethylenedioxy)dibenzamidine
pentamidin
pentamidine

Definition

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

References

beilstein:3159790
cas:100-33-4
drugbank:DB00738
drugcentral:2090
hmdb:HMDB0014876
kegg.compound:C07420
kegg.drug:D08333
lincs.smallmolecule:LSM-4540
patent:EP975608
patent:GB507565
patent:US2006235001
patent:US2008167296
patent:US2008214569
patent:US2394003
patent:US7115665
pdb-ccd:PNT
pubmed:10415905
pubmed:10917591
pubmed:11438428
pubmed:11584934
pubmed:14603035
pubmed:15711592
pubmed:18346045
pubmed:18971316
pubmed:19966562
pubmed:20144237
pubmed:20599360
pubmed:22046004
pubmed:22093811
pubmed:22200378
pubmed:22327112
pubmed:26052915
pubmed:26117647
pubmed:26295040
pubmed:26344166
pubmed:26418240
pubmed:26431253
pubmed:26515653
pubmed:26606757
pubmed:26648589
pubmed:26734860
pubmed:26824946
pubmed:26828608
pubmed:26882015
pubmed:26903605
pubmed:26938448
pubmed:27011917
pubmed:27135970
pubmed:27164533
pubmed:27214074
pubmed:27297108
pubmed:27353022
pubmed:27357655
pubmed:27600039
pubmed:27729250
pubmed:28074607
pubmed:28167598
pubmed:28263303
pubmed:7542607
pubmed:7690919
pubmed:8841838
reaxys:3159790
wikipedia.en:Pentamidine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from pentamidine

Phenotype where environments contain pentamidine

Phenotype modified by environments containing pentamidine

Phenotype affecting pentamidine

Human Disease Model