propafenone

Term ID

CHEBI:63619

Synonyms

• 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone
• 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one
• 2-(2'-hydroxy-3'-propylaminopropoxy)-omega-phenylpropiophenone
• propafenona
• propafenone
• propafenonum

Definition

An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

References

• cas:54063-53-5
• drugbank:DB01182
• drugcentral:2291
• kegg.compound:C07381
• kegg.drug:D08435
• lincs.smallmolecule:LSM-1416
• patent:DE2001431
• pubmed:8777484
• reaxys:2175182
• wikipedia.en:Propafenone

Ontology

ChEBI  ( EBI )

Resources

CTD