manzamine A

Term ID

CHEBI:66667

Synonyms

• (4aR,7S,7aR,13Z,14aR,15aR,18Z)-5-(9H-beta-carbolin-1-yl)-4,4a,9,10,11,12,14a,15-octahydro-3H-7,2-oct[3]enoazocino[1',2':1,5]pyrrolo[2,3-i]isoquinolin-7(1H,7aH)-ol

Definition

An alkaloid of the class of β-carbolines isolated from Haliclona and Acanthostrongylophora. It exhibits inhibitory activity against Glycogen Synthase Kinase-3 (EC 2.7.11.26).

References

• cas:104196-68-1
• patent:US2012289533
• pubmed:10817722
• pubmed:17708655
• pubmed:18520099
• pubmed:20017491
• pubmed:20352293
• pubmed:20645244
• pubmed:23039372
• pubmed:8158160
• reaxys:4625288

Ontology

ChEBI  ( EBI )

Resources

CTD