Search Ontology:
ChEBI

dactolisib

Term ID
CHEBI:71952
Synonyms
  • 2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
  • BEZ 235
  • BEZ-235
  • BEZ235
  • NVP BEZ235
  • NVP-BEZ 235
  • NVP-BEZ235
  • NVPBEZ235
Definition
An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.
References
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from dactolisib
Phenotype where environments contain dactolisib
Phenotype modified by environments containing dactolisib
Phenotype affecting dactolisib
Human Disease Model
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