eliglustat

Term ID

CHEBI:82752

Synonyms

• eliglustat
• Genz 99067
• Genz-99067
• N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide

Definition

A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltransferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.

References

• cas:491833-29-5
• drugcentral:4834
• kegg.drug:D09893
• pubmed:20439622
• pubmed:20713962
• pubmed:20864621
• pubmed:20872320
• pubmed:22563139
• pubmed:24816856
• pubmed:24835462
• pubmed:25239269
• reaxys:21475293
• wikipedia.en:Eliglustat

Ontology

ChEBI  ( EBI )